Canada approves E coli vaccine for cattle

first_img Tony Milici, MD, PhD, GeneThera’s chairman, said in the statement that the company will launch phase 2 clinical trials shortly. “Our goal is to take the vaccine to market as soon as possible,” he added. Brett Finlay, a microbiologist at the University of British Columbia whose research led to development of the vaccine, said in an Oct 27 Bioniche press release, “If we block the colonization of cows by O157, we basically decrease the number that humans are exposed to, and thus, dropping disease levels in humans.” Bioniche is also positioning itself to market the vaccine to cattle producers in the United States, according to a previous report. In February, the US Department of Agriculture (USDA) notified the company that the latest data on the vaccine met its “expectation of efficacy” standard, which allowed the company to pursue a conditional US license. The vaccine contains live attenuated bacteria developed by Edgar Boedeker, an internal medicine professor at UNM, and Chengru Zhu, formerly of UNM and now chief of environmental microbiology at the Maryland Department of Health, according to a GeneThera statement. The vaccine is designed to inhibit the carriage and shedding of enterohemorrhagic E coli such as O157:H7. ‘A missing link’Bill Clark, a nephrologist at the London Health Sciences Centre in London, Ont., said that an E coli O157:H7 vaccine isn’t a firewall against food contamination, according to an Oct 28 report from the Canadian Broadcasting Corporation (CBC). “I’m not sure any one solution will do it, and I certainly think people still have to be very careful with their food practices,” he told the CBC. Nov 3, 2008 (CIDRAP News) – Bioniche Life Sciences, based in Belleville, Ont., announced recently that it received full approval from the Canadian Food Inspection Agency (CFIA) to market the world’s first vaccine to reduce Escherichia coli O157:H7 shedding by cattle, a measure that could decrease contamination in meat and produce. E coli O157:H7 doesn’t sicken cattle but is potentially fatal to humans. It produces a toxin that causes diarrhea, often bloody, but usually no fever. Though most patients with E coli O157:H7 infections recover in 5 to 10 days, 2% to 7% develop hemolytic uremic syndrome, a potentially fatal form of kidney failure. The vaccine, called Econiche, will be produced at Bioniche’s Belleville facility, which is undergoing a $25 million expansion. The company said vaccine supplies would be limited during the expansion period. Oct 27 Bioniche press release about vaccine’s approval Oct 17 Bioniche press release about study of vaccine US company eyes cattle vaccineOn the same day Bioniche announced it had received full Canadian approval, a US company, GeneThera, Inc, based in Wheat Ridge, Colo., announced that it had signed an agreement with the University of New Mexico’s (UNM’s) technology transfer arm to license and distribute a cattle  E coli vaccine developed at the UNM Health Sciences Center. Smith DR, Moxley RA, Peterson RE, et al. A two-dose regimen of a vaccine against Escherichia coli O157:H7 type III secreted proteins reduced environmental transmission of the agent in a large-scale commercial beef feedlot clinical trial. Foodborne Pathogens and Disease 2008 Oct 1;5(5):589-98 [Abstract] Kym Anthony, a specialty beef producer in Clarksburg, Ont., said in the Bioniche press release that he has been using the vaccine over the past year under a conditional Canadian permit. “We’ve been trying to do our part to be an industry leader in food safety. The E coli vaccine fits into that,” Anthony said. “It’s been a missing link in the industry so far.” See also: The company said the vaccine could also be used in livestock at petting zoos and agricultural expositions to reduce bacterial transmission to humans. However, some producers may find the cost prohibitive. Rick Holley, a professor of food safety and microbiology at the University of Manitoba, told the CBC, “So long as these organisms don’t make the animals sick, you’re not going to see a great deal of incentive to move toward prevention.” The company did not list a cost for the vaccine, but officials previously told CIDRAP News that a course of the vaccine would likely cost less than $10 per head of cattle. As approved by the CFIA, the course involves three doses, but a study published in the October issue of Foodborne Pathogens and Disease showed that a two-dose regimen reduced the probability of environmental transmission of E coli O157:H7 within a large-scale cattle feeding operation.last_img read more

Tyler Zeller looking forward to USA Basketball debut

first_imgLATEST STORIES Tim Cone, Ginebra set their sights on elusive All-Filipino crown Before flying to Argentina on Sunday night, the Americans gathered in Houston for a few practices. Clinching scenarios weren’t exactly discussed in great detail, and players’ focus was largely kept on Thursday night’s test in La Rioja — where as many as 11,000 Argentines will fill an arena to root against the U.S.“They know where we stand, and they know we’re going to need to win two more games to qualify,” U.S. coach Jeff Van Gundy said.The G League has provided most of the players that the U.S. has used in qualifying so far, and that will be the case again this time with 10 players coming from those clubs. The other two are free agents — Eric Moreland, who appeared in 67 games with Detroit last season, and Zeller, a vet of 406 NBA games with four different teams.Zeller, 28, was waived by Milwaukee during the preseason. He has also played for Boston, Cleveland and Brooklyn during his NBA career. Van Gundy said these two games will be a chance for Zeller to show he belongs back in the league.“Some guys have never been in the NBA and want to get there and other guys like Tyler have been there and want to get back,” Van Gundy said. “For Tyler, it’s important that he show the NBA people that the thing they’re most concerned about, which is probably his pick-and-roll defense, is capable of standing up against NBA competition.”ADVERTISEMENT Allen Durham still determined to help Meralco win 1st PBA title Lights inside SMX hall flicker as Duterte rants vs Ayala, Pangilinan anew MOST READ The 7-foot Zeller will likely get matched up plenty Thursday against a familiar face: Longtime NBA player Luis Scola leads Argentina.“It’s a great opportunity,” Zeller said. “We’re going against two of the better FIBA teams in the world on this trip, we get to go compete at a high level and I think everybody here is excited about that.”Sports Related Videospowered by AdSparcRead Next Ginebra beats Meralco again to capture PBA Governors’ Cup title Don’t miss out on the latest news and information. When USA Basketball resumes its quest to qualify for the 2019 FIBA World Cup, Zeller will be wearing the red, white and blue in an international game for the first time. The NBA veteran and current free agent is one of the 12 players on the squad for this two-game window of qualifying, which starts with a crucial matchup Thursday at Argentina.“Obviously, I just love to play,” said Zeller, who played for four NBA teams after leaving North Carolina in 2012. “When they called and asked if I wanted to play, I told them I’d love to. Hopefully I can get on an NBA team, play well and somebody will pick me up after. But at the end of the day, I just love to play basketball and I want to go compete for our country and try to get them qualified on this trip.”FEATURED STORIESSPORTSGinebra beats Meralco again to capture PBA Governors’ Cup titleSPORTSJapeth Aguilar wins 1st PBA Finals MVP award for GinebraSPORTSGolden State Warriors sign Lee to multiyear contract, bring back ChrissThe U.S. is on the brink of clinching one of the 32 spots for the World Cup, with a 7-1 record in qualifying so far and tied for first with Argentina in Group E of the Americas qualifying. They’re in a six-team division for this round, and the top three finishers in that division are automatically assured of a berth.The U.S.-Argentina winner will have a three-game lead over the fourth-place team with three games left, so Thursday’s outcome looms large. If the U.S. goes 2-0 on this trip — the Americans visit Uruguay on Sunday — the World Cup spot will be clinched. A 1-1 record could assure a spot as well, depending on outcomes of other games in this qualifying window. Gov’t to employ 6,000 displaced by Taal Nadine Lustre’s phone stolen in Brazil Ex-NBA star Dikembe Mutombo moved to tears in Jerusalem Gretchen Barretto’s daughter Dominique graduates magna cum laude from California college Carpio hits red carpet treatment for China Coast Guard PLAY LIST 02:14Carpio hits red carpet treatment for China Coast Guard02:56NCRPO pledges to donate P3.5 million to victims of Taal eruption00:56Heavy rain brings some relief in Australia02:37Calm moments allow Taal folks some respite03:23Negosyo sa Tagaytay City, bagsak sa pag-aalboroto ng Bulkang Taal01:13Christian Standhardinger wins PBA Best Player award Lights inside SMX hall flicker as Duterte rants vs Ayala, Pangilinan anew FILE – In this Oct. 12, 2018, file photo, Milwaukee Bucks center Tyler Zeller, left, looks to shoot as Minnesota Timberwolves center Gorgui Dieng defends during an NBA preseason basketball game in Milwaukee. When USA Basketball resumes its quest to qualify for the 2019 FIBA World Cup, Zeller will be wearing the red, white and blue in an international game for the first time. The NBA veteran and current free agent is one of the 12 players on the squad for this two-game window of qualifying, which starts with a crucial matchup Thursday at Argentina.(AP Photo/Mike Roemer, File)Tyler Zeller spent the last few weeks waiting for a team to call.His country came through.ADVERTISEMENT Japeth Aguilar embraces role, gets rewarded with Finals MVP plum View commentslast_img read more

White night not enough to save USC

first_img AD Quality Auto 360p 720p 1080p Top articles1/5READ MORECoach Doc Rivers a “fan” from way back of Jazz’s Jordan Clarkson White lingered on the field long after an MVP-type performance in which he scored three touchdowns and ran for 124 yards on 20 carries. He soaked in the atmosphere of what could’ve been his final game with family and friends. White, a junior, will take about a week to decide if he’s turning pro but it will take a lot longer to erase that fourth-and-2. “I’ve got some thinking to do,” White said. “I have to talk things over with my family. I don’t want to bail out but there’s a lot of money there and NFL dreams out there. It’s a big decision. I’ll lean on some people, but ultimately I’ll go with my heart. I don’t think my heart will let me down.” White didn’t let USC down and athletic director Mike Garrett made sure to let White know as much. As White tried to hold back tears, Garrett told him: “You were a monster out there. Don’t get down. What you showed is all you need to show.” Like that play when White ran down the sideline and stiff-armed Michael Huff in the second quarter. He shoved him backward by the face mask and tossed him to the ground and was tackled at Texas’ 3. He scored on the next play to give USC a 17-16 lead. He gave USC a 24-23 lead just before halftime with a 12-yard score and high-stepped his way into the end zone. Texas and the rest of the free world was preoccupied with finding a way to contain Reggie Bush, who ran for a 26-yard score and 82 yards on 13 carries. White and Bush have been such a potent combination. Well-known as “Thunder and Lightning”, the duo set a combined record for 99 career touchdowns, eclipsing the previous mark set by Army’s Doc Blanchard and Glenn Davis, who combined for 97 career touchdowns from 1943-46. This time, the combination wasn’t bigger than Texas. White was tackled for a 1-yard gain and USC turned the ball over on downs to Texas. The Longhorns then turned it over to Vince Young and Texas won a thrilling national championship, 41-38. Pete Carroll momentarily hid the tears in LenDale White’s eyes with an emotional embrace. Carroll leaned on White for several seconds, much like he leaned on him in the Rose Bowl. White’s power game worked like magic against Texas. But on fourth-and-2 and needing only a first down to ice the game, Carroll went for it and put the game in the hands the offensive line and White. center_img A two-headed monster, indeed. Texas couldn’t stop White, but USC couldn’t stop Young, either. And that’s why the loss was so hard to fathom. In White’s career at USC, he’s 37-2. Winning became a habit. Losing wasn’t. “I haven’t lost in a long time,” White said. “But it’s easy for me to walk around with my head up high.” He just might not be doing it around the USC campus next year. Jill Painter, (818) 713-3615 jill.painter@dailynews.com 160Want local news?Sign up for the Localist and stay informed Something went wrong. Please try again.subscribeCongratulations! You’re all set!last_img read more